The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 1997

Filed:

Jun. 05, 1995
Applicant:
Inventors:

Kenneth T Dickerson, San Diego, CA (US);

James R Glass, Cardiff, CA (US);

Lin-Shu Liu, Mountain View, CA (US);

James W Polarek, Del Mar, CA (US);

William S Craig, San Diego, CA (US);

Daniel G Mullen, San Diego, CA (US);

Soan Cheng, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
514-8 ; 514 13 ; 514 14 ; 514 15 ; 514 16 ; 514 17 ; 530322 ; 530326 ; 530327 ; 530328 ; 530329 ; 530330 ; 530345 ; 530411 ;
Abstract

The present invention provides novel conjugates of a synthetic polypeptide containing RGD or (dR)GD and a biodegradable polymer, hyaluronate. The conjugates are prepared by any one of three different methods provided by the present invention: (1) an epoxide method (2) a sodium periodate method, and (3) a tresyl chloride method. The conjugates prepared by these methods are useful to aid in wound healing and tissue regeneration by providing a temporary matrix for tissue repair. The invention also provides novel RGD-peptides.


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