The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 1997

Filed:

May. 26, 1995
Applicant:
Inventors:

Brent Blackburn, San Francisco, CA (US);

Peter Barker, El Granada, CA (US);

Thomas Gadek, Oakland, CA (US);

Robert McDowell, San Francisco, CA (US);

Lawrence McGee, Pacifica, CA (US);

Todd Somers, Montara, CA (US);

Rob Webb, Moss Beach, CA (US);

Kirk Robarge, San Francisco, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514211 ; 540490 ; 540552 ; 540523 ; 540580 ; 540593 ; 540495 ; 540506 ; 540493 ; 540504 ; 540512 ; 514215 ; 514219 ; 514220 ; 514221 ;
Abstract

A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.


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