The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 1997
Filed:
May. 25, 1995
Applicant:
Inventors:
William F Heath, Jr, Fishers, IN (US);
John H McDonald, III, Carmel, IN (US);
Michael Paal, Hamburg, DE;
Theo Schotten, Vierhofen, DE;
Wolfgang Stenzel, Reinbek, DE;
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07H / ;
U.S. Cl.
CPC ...
514414 ; 514411 ; 514 32 ; 548428 ; 548455 ; 548466 ; 536 173 ;
Abstract
The present invention discloses compounds that are highly isozyme selective protein kinase C beta-1 and beta-2 isozyme inhibitors. Accordingly, the present invention provides a method of selectively inhibiting protein kinase C isozymes beta-1, and beta-2. As isozyme selective inhibitors of beta-1 and beta-2, the compounds are therapeutically useful in treating conditions associated with diabetes mellitus and its complications, as well as other disease states associated with an elevation of the beta-1 and beta-2 isozyme.