The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 1997
Filed:
Dec. 11, 1995
Michael C Chikindas, Bromborough, GB;
Andrew Joiner, Liverpool, GB;
Philip William Small, Bromborough, GB;
Chesebrough-Pond's USA Co., Division of Conopco, Inc., Greenwich, CT (US);
Abstract
The present invention relates to anti-microbial cosmetic compositions for the care of the human body or parts thereof, comprising derivatives of histatins or fragments thereof. It has been found that the anti-microbial activity of histatins or their fragments can be significantly enhanced by capping them at the C-terminus or at the C- and N-terminus and/or complexing them with anti-microbially-active metal ions. The thus modified histatins and histatin fragments were found to have a significantly increased activity against a range of microbial strains, and were found to be useful as controlled delivery agents for the metal ions. They are suitable for a whole range of anti-microbial applications, such as anti-plaque, and-caries, anti-bad breath oral applications, deodorant applications, personal hygiene applications and so on, for which they are included in any suitable carrier medium. Preferred are the capped derivatives, which have been complexed with Ag, Cu, Zn or Sn.