The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 1997
Filed:
Jun. 01, 1995
Applicant:
Inventors:
Charles A Marotta, Cambridge, MA (US);
Ronald E Majocha, Needham, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C12N / ;
U.S. Cl.
CPC ...
536 231 ; 536 235 ;
Abstract
The invention provides oligonucleotides that inhibit the expression of .beta./A4 peptide of Alzheimer's disease and Down's syndrome, and further provides methods for reversing morphological changes caused in neuronal cells by .beta./A4 peptide.