The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 1997
Filed:
Nov. 28, 1994
Applicant:
Inventors:
Masaaki Matsuo, Toyonaka, JP;
Daijiro Hagiwara, Moriguchi, JP;
Takashi Manabe, Kawanishi, JP;
Nobukiyo Konishi, Nagaokakyo, JP;
Shinji Shigenaga, Kobe, JP;
Kenji Murano, Osaka, JP;
Hiroshi Matsuda, Osaka, JP;
Hiroshi Miyake, Kyoto, JP;
Assignee:
Fujisawa Pharmaceutical Co., Ltd., Osaka, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514253 ; 514218 ; 514252 ; 514254 ; 514255 ; 540575 ; 544121 ; 544357 ; 544360 ; 544364 ; 544367 ; 544373 ; 544376 ; 544379 ; 544385 ; 544387 ; 544388 ; 544391 ; 544403 ; 548495 ; 549 58 ; 560 27 ; 560 28 ;
Abstract
A piperazine compound of the formula: ##STR1## wherein: X is carbonyl or sulfonyl; Y is a direct bond or lower alkylene; and R.sub.1, R.sub.2, R.sub.3, R.sub.4 are as defined herein. The compounds are advantageously used as Tachykinin antagonists in the treatment of respiratory diseases, ophthalmic diseases and inflammatory diseases, for example.