The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 1997
Filed:
Aug. 29, 1994
Applicant:
Inventors:
Richard M Harland, Berkeley, CA (US);
William C Smith, Oakland, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
514 42 ; 514 13 ; 514 14 ; 514 21 ; 530399 ; 530326 ; 530327 ; 435 691 ;
Abstract
A novel and soluble polypeptide that is highly conserved among vertebrates has been discovered, which is designated 'noggin.' The properties of noggin include dorsal growth inducing activity. Noggin and activin act synergistically to produce dorsal mesoderm. Noggin's cDNA has been cloned. Several expression systems have been successfully used to express biologically active noggin. Amino acid sequences representing completely conserved portions as between frog noggin and mouse noggin are: