The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 1997
Filed:
Apr. 21, 1995
Applicant:
Inventors:
Ian Richard Buxton, Cambridge, GB;
Helen Critchley, Cambridge, GB;
Stewart Thomas Leslie, Cambridge, GB;
Derek Allan Prater, Cambridge, GB;
Ronald Brown Miller, Basel, CH;
Sandra Therese Malkowska, Cambridge, GB;
Assignee:
Euro-Celtique, S.A., Luxembourg, LU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
424495 ; 424494 ; 424497 ; 424498 ; 424499 ; 514781 ;
Abstract
A controlled release composition including spheroid cores of diltiazem or a pharmaceutically acceptable salt thereof and optionally a spheronizing agent, the cores being coated with a controlled release layer, and a method of manufacturing the same, is disclosed. The spheronizing agent when present is preferably microcrystalline cellulose. Ethylcellulose is a preferred release coating. The controlled release coating preferably contains a plasticizer, a surfactant and a tack-modifier.