The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 1997
Filed:
Oct. 18, 1996
Scott W Bagley, Groton, CT (US);
Theodore P Broten, Ambler, PA (US);
Prasun K Chakravarty, Edison, NJ (US);
Daljit S Dhanoa, Secaucus, NJ (US);
Kenneth J Fitch, Cranford, NJ (US);
William J Greenlee, Teaneck, NJ (US);
Nancy Jo Kevin, Clifton, NJ (US);
Gerard R Kieczykowski, Westfield, NJ (US);
Douglas J Pettibone, Chalfont, PA (US);
James R Tata, Westfield, NJ (US);
Ralph A Rivero, Tinton Falls, NJ (US);
Thomas F Walsh, Westfield, NJ (US);
David L Williams, Jr, Telford, PA (US);
Jay M Matthews, Fords, NJ (US);
Richard B Toupence, Cranford, NJ (US);
Merck & Co. Inc., Rahway, NJ (US);
Abstract
Phenoxyphenylacetic acids and derivatives of the general structural formula I ##STR1## have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.