The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 1997
Filed:
Jun. 07, 1995
Richard R Tidwell, Pittsboro, NC (US);
James E Hall, Chapel Hill, NC (US);
David W Boykin, Atlanta, GA (US);
Christine C Dykstra, Chapel Hill, NC (US);
John Perfect, Durham, NC (US);
Byron L Blagburn, Auburn, AL (US);
Duke University, Durham, NC (US);
Auburn University, Auburn, AL (US);
Georgia State University, Atlanta, GA (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
The present invention provides methods for treating Cryptococcus neoformans, Cryptosporidium parvum, and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a compound of Formula I: ##STR1## wherein: X is located in the para or meta positions and is loweralkyl, loweralkoxy, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, alkylaryl, halogen, or ##STR2## wherein: each R.sub.2 is independently selected from the group consisting of H, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl or two R.sub.2 groups together represent C.sub.2 -C.sub.10 alkylene, or two R.sub.2 groups together represent ##STR3## wherein m is from 1-3 and R.sub.4 is H, ##STR4## or --CONHR.sub.5 NR.sub.6 R.sub.7, wherein