The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 1997
Filed:
May. 07, 1996
Applicant:
Inventors:
John Michael Domagala, Canton, MI (US);
Helen Tsenwhei Lee, Ann Arbor, MI (US);
Randy Ranjee Ramharack, Ann Arbor, MI (US);
Bruce David Roth, Ann Arbor, MI (US);
Tomi Sawyer, Ann Arbor, MI (US);
Drago Robert Sliskovic, Saline, MI (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514373 ; 514258 ; 514301 ;
Abstract
Plasma levels of Lp(a) are lowered by administering an isothiazolone having the general structure ##STR1## where A is a monocyclic or bicyclic ring which may contain up to 3 heteroatoms selected from O, S, and N; R.sup.1 and R.sup.2 are substituent groups such as alkyl, alkoxy, hydroxy, nitro, cyano, amino, and carboxy; and R.sup.5 is alkyl, cycloalkyl, phenyl, and Het.