The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 1997

Filed:

Sep. 11, 1991
Applicant:
Inventors:

Teiji Kimura, Ibaraki, JP;

Nobuhisa Watanabe, Ibaraki, JP;

Yasutaka Takase, Ibaraki, JP;

Kenji Hayashi, Ibaraki, JP;

Makoto Matsui, Ibaraki, JP;

Hironori Ikuta, Ibaraki, JP;

Youji Yamagishi, Ibaraki, JP;

Kozo Akasaka, Ibaraki, JP;

Hiroshi Tanaka, Ibaraki, JP;

Issei Ohtsuka, Ibaraki, JP;

Takao Saeki, Ibaraki, JP;

Motoji Kogushi, Ibaraki, JP;

Tohru Fujimori, Tenafly, NJ (US);

Isao Saito, Ibaraki, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514255 ; 514256 ; 514277 ; 514315 ; 514359 ; 514381 ; 514399 ; 514403 ; 514408 ; 514597 ; 514598 ; 544335 ; 544398 ; 544402 ; 544403 ; 546192 ; 546329 ; 546330 ; 564 48 ; 564 49 ; 564 51 ; 564 52 ;
Abstract

A benzene, pyridine or pyrimidine derivative having the below shown formula is novel and useful as an anti-arteriosclerotic agent. ##STR1## wherein R.sup.1 stands for a lower alkyl group, an amino group which may be substituted, or the like; R.sup.2 stands for a group represented by the formula: ##STR2## (wherein R.sup.16 stands for an alkyl group having 1 to 6 carbon atoms, or the like) or the like; R.sup.3 stands for a group represented by the formula: --O--(CH.sub.2).sub.m --Y (Y stands for an imidazolyl or piperazinyl group, or the like and m is 1 to 6) or the like; R.sup.5 stands for a hydrogen atom, a lower alkyl group, or the like; A stands for a group represented by the formula: ##STR3## (wherein R.sup.6 stands for a hydrogen atom, a lower alkyl group, or the like), --N.dbd., or the like; and B stands for a group represented by the formula: ##STR4## (wherein R.sup.4 stands for a hydrogen or the like), --N.dbd., or the like.


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