The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 1997
Filed:
Nov. 04, 1991
Cecille Rochette-Egly, Strasbourg, FR;
Yves Lutz, Strasbourg, FR;
Michael Saunders, Ostwald, FR;
Isabelle Scheuer, Hagulnau, FR;
Marie-Pierre Gaub, Strasbourg, FR;
Pierre Chambon, Blaesheim, FR;
Institut National de la Sante et de la Recherche Medicale, Paris, FR;
Centre National de la Recherche Scientifique, Paris, FR;
Universite Louis Pasteur, Strasbourg I, Paris, FR;
E.R. Squibb & Sons, Inc., Princeton, NJ (US);
Abstract
The present invention discloses methods for preparing antibodies which bind to specific isoforms of the human retinoic acid receptor-.gamma. (RAR-.gamma.). In addition, several monoclonal antibodies are described which bind to human RAR-.gamma., but not to mouse or which bind to RAR-.gamma.1, but not to RAR-.gamma.2. Methods and kits are described which allow one to detect the isotype of RAR-.gamma. which is expressed in a test sample. Such methods are useful in determining the tissue specific pattern of expression of various RAR-.gamma. isoforms.