The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 1997

Filed:

Nov. 30, 1994
Applicant:
Inventors:

Roland Ekerdt, Berlin, DE;

Georg Raptis, Berlin, DE;

Alfred Pauls, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514572 ; 514573 ; 514510 ; 514561 ; 514469 ;
Abstract

The invention relates to a dermal application form of prostacyclin derivatives of Formula I ##STR1## wherein R.sub.1 means hydrogen or alkyl of 1-10 carbon atoms, A is a --CH.sub.2 --CH.sub.2 --, trans-CH.dbd.CH-- or --C.ident.C-group, W represents a hydroxymethyl group which is free or functionally modified at the hydroxy group, the OH-group being in the .alpha.- or .beta.-position, X is a CH.sub.2 -group or an oxygen atom, Z is hydrogen or a cyano group, D means a straight-chain or branched, saturated alkylene group of 1-5 carbon atoms, E is a --C.ident.C-linkage or a direct bond, R.sub.2 is a straight- or branched-chain, saturated alkyl group of 1-7 carbon atoms, R.sub.3 is a free or functionally modified hydroxy group, and, if R.sub.1 means a hydrogen atom, containing the salts thereof with physiologically compatible bases, for the treatment of ulcerations caused by arterial occlusive diseases, and other skin disorders.


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