The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 1997
Filed:
Nov. 15, 1993
Applicant:
Inventors:
Philip J Barr, Berkeley, CA (US);
John P Shapiro, Albany, CA (US);
Michael C Kiefer, Clayton, CA (US);
Assignee:
LXR Biotechnology Inc., Richmond, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ;
U.S. Cl.
CPC ...
435325 ; 536 235 ; 4353201 ; 4352523 ; 43525411 ; 435 691 ; 435348 ; 435361 ; 435358 ;
Abstract
The invention provides soluble forms of the Fas (Apo-1 ) protein comprising both the intracellular and extracellular domains of the full-length polypeptide. Exemplified is a naturally-occurring splice variant of the Fas gene, Fas.DELTA.TM, which lacks the transmembrane domain of the native antigen. DNA encoding the protein, cells expressing the recombinant DNA, and methods of using the protein and DNA are also provided.