The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 1997

Filed:

Dec. 08, 1995
Applicant:
Inventors:

Bryan L Ray, Burlington, MA (US);

Edmund C Lin, Boston, MA (US);

Roberto Crea, Belmont, MA (US);

Assignee:

Medical Science Partners, Wellesley, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07H / ; C07K / ;
U.S. Cl.
CPC ...
4352351 ; 435239 ; 536 2372 ; 530402 ;
Abstract

Disclosed is a protein construct including a chemically modified lambdoid tail protein having a chemically reactive amino acid residue linked to a target molecule. Also disclosed is an infective lambdoid bacteriophage displaying on its outer surface the chemically modified tail protein. In addition, methods of detecting a molecule-of-interest in a solution and methods of detecting cells producing a molecule-of-interest which utilize the infective lambdoid bacteriophage having the chemically modified tail protein are disclosed.


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