The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 1997
Filed:
Nov. 02, 1994
Alfred Joseph Moo-Young, Hastings-On-Hudson, NY (US);
The Population Council, Center for Biomedical Research, New York, NY (US);
Abstract
Disclosed is a subdermally implantable drug-delivery device, which contains: a central core extending in an axial direction and having an outer surface and opposing ends, which core includes a matrix of a pharmaceutically effective amount of a subdermally administrable drug substantially uniformly dispersed in a polymeric base material; an intermediate polymeric layer overlying the outer surface of the central core; and an outer polymeric layer overlying the intermediate layer, wherein the intermediate layer controls the rate of diffusion of the drug from the central core to the outer layer. In preferred embodiments, the subdermally administrable drug is a contraceptive agent such as the 16-methylene-17-.alpha.-acetoxy-19-norprogesterone progestin; the polymeric base material and the outer polymeric layer each contain a polydimethylsiloxane such as Silastic.RTM.; and the intermediate layer contains a porous material such as cellulose. The devices provide for the substantially zero-order release of the drug for their intended lifetime without initial overdosing of the drug.