The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 1997
Filed:
Jan. 05, 1996
Applicant:
Inventors:
Igor V Kutyavin, Bothell, WA (US);
Eugeny A Lukhtanov, Bothell, WA (US);
Howard B Gamper, Bothell, WA (US);
Rich B Meyer, Jr, Bothell, WA (US);
Alexander Gall, Bothell, WA (US);
Assignee:
Epoch Pharmaceuticals, Inc., Bothell, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C07H / ; A01N / ;
U.S. Cl.
CPC ...
536 221 ; 536 231 ; 536 243 ;
Abstract
Covalently linked conjugates of oligonucleotides (ODNs) with a cyclopropapyrroloindole moiety or an analog thereof, selectively and efficiently alkylate and crosslink with nucleic acid sequences that are complementary to the base sequence of the ODN.