The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 1997

Filed:

Jan. 14, 1994
Applicant:
Inventors:

Jemo Kang, Princeton, NJ (US);

John A Colanduoni, Bridgewater, NJ (US);

Dong Joon Lee, Seoul, KR;

Byungwoo Youn, Wyckoff, NJ (US);

Chiyoung Ok, Seoul, KR;

Walter J Kang, Princeton, NJ (US);

Assignee:

Princeton Biomeditech Corporation, Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-794 ; 422 56 ; 422 57 ; 435-79 ; 435-792 ; 435 21 ; 435 26 ; 435 28 ; 435962 ; 435963 ; 435970 ; 435975 ; 4352872 ; 4352877 ; 435805 ; 435810 ; 436518 ; 436527 ; 436530 ; 436531 ; 436169 ; 436808 ; 436810 ;
Abstract

The invention pertains to dipstick immunoassay devices. The device comprises a base member and a single, combined sample contact zone and test zone, wherein the test zone incorporates the use of symbols to detect analytes in a sample of biological fluid. A first immunological component, an anti-immunoglobulin capable of binding to an enzyme-labeled antibody, is immobilized in a control indicia portion. A second immunological component, capable of specifically binding to a target analyte which is bound to the enzyme-labeled antibody to form a sandwich complex, is immobilized in a test indicia portion. The enzyme-labeled antibody produces a visual color differential between a control indicia portion and a non-indicia portion in the test zone upon contact with a substrate. The device additionally includes a first polyol and a color differential enhancing component selected from the group consisting of an inhibitor to the enzyme and a competitive secondary substrate for the enzyme distributed throughout the non-indicia portion of the test zone.


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