The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 1997
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Rolf Lohrmann, La Jolla, CA (US);
Dung K Hong, San Diego, CA (US);
Assignee:
Molecular Biosystems, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G07C / ;
U.S. Cl.
CPC ...
554 37 ; 554 51 ; 554 55 ; 554 56 ; 554 61 ; 554 62 ; 554 63 ; 554 67 ; 554103 ; 554104 ; 554107 ; 554121 ; 554123 ; 554225 ; 554226 ; 554220 ; 554218 ; 554213 ; 560-8 ; 560 19 ; 560 37 ; 560 38 ; 560 47 ; 560103 ; 560105 ; 560110 ;
Abstract
Aromatic acid-derived lipophilic polyhalogenated compounds are provided for use as contrast agents in diagnostic imaging or as therapeutic agents. These compounds are particularly useful when incorporated into an oil-in-water emulsion for tissue-specific delivery to the liver. For hepatocyte-selective delivery, the emulsion is chylomicron remnant-like by being in a size range of 50 to 200 nm and having a composition simulating naturally-occuring chylomicron remnants.