The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 1997
Filed:
May. 04, 1995
Applicant:
Inventors:
Woo-Baeg Choi, North Brunswick, NJ (US);
Guy R Humphrey, Belle Mead, NJ (US);
Paul J Reider, Westfield, NJ (US);
Ichiro Shinkai, Westfield, NJ (US);
Andrew S Thompson, Mountainside, NJ (US);
Ralph P Volante, Cranberry, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07F / ;
U.S. Cl.
CPC ...
540200 ;
Abstract
The present invention is directed to a process of making a Beta-methyl carbapenem intermediate of formula VI from a compound of formula I ##STR1## wherein R and P' are protecting groups R.sup.1 is a methylmalonic acid ester and Nu is a nucleophilic group. Process intermediates are also disclosed.