The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 1997
Filed:
Feb. 10, 1995
Applicant:
Inventors:
Terukage Hirata, Hiroshima, JP;
Nobuya Sakae, Hiroshima, JP;
Koichi Tamura, Hiroshima, JP;
Masayasu Okuhira, Hiroshima, JP;
Hirotaka Amano, Hiroshima, JP;
Masaharu Yokomoto, Hiroshima, JP;
Jun Nomiyama, Hiroshima, JP;
Assignee:
Wakunaga Seiyaku Kabushiki Kaisha, Osaka, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514363 ; 548138 ;
Abstract
This invention relates to a biphenylmethane derivative represented by the formula (1): ##STR1## wherein A represents a group ##STR2## in which R.sup.1, X, Y, Z and B are as defined in the Specification. The compounds have potent angiotensin II antagonist activity and anti-hypertensive effect. They have therapeutic utility for circulatory diseases such as hypertension, heart diseases and cerebral apoplexy.