The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 1997
Filed:
Jun. 06, 1995
Anthony H Ingall, Leicestershire, GB;
Peter A Cage, Leicestershire, GB;
Astra Pharmaceuticals Limited, Hertfordshire, GB;
Abstract
There are disclosed compounds of formula I, ##STR1## wherein Q represents CR.sup.1 R.sup.2, R represents O or CR.sup.3 R.sup.4, W represents O or CH.sub.2, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently represent hydrogen or halogen, X represents S(O).sub.n R.sup.5, alkyl C.sub.1-6 alkoxy C.sub.1-6, acylamino C.sub.1-6, CONR.sup.6 R.sup.7, NR.sup.8 R.sup.9, halogen, a 5- or 6-membered S containing heterocycle, or phenyl optionally substituted by alkyl C.sub.1-6, n represents 0, 1 or 2, R.sup.5 represents aryl or alkyl C.sub.1-6 optionally substituted by one or more substituents selected from hydroxy, alkoxy C.sub.1-6, halogen and aryl; R.sup.6, R.sup.7, R.sup.8 and R.sup.9 independently represent hydrogen or alkyl C.sub.1-6, Y represents NH.sub.2 or alkoxy C.sub.1-6, and Z represents an acidic moiety, in addition, when R represents CR.sup.3 R.sup.4, then --Q--Z may also represent hydroxy or --OP(O)(OH).sub.2, and pharmaceutically acceptable salts thereof, with certain provisos, for use as pharmaceuticals.