The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 1997

Filed:

Jun. 06, 1995
Applicant:
Inventors:

Peng Cho Tang, Moraga, CA (US);

Daniel Emil Levy, Alameda, CA (US);

Kevin Ross Holme, Alameda, CA (US);

Saeed Abdalla Abbas, Vallejo, CA (US);

Assignee:

Glycomed Incorporated, Alameda, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07H / ;
U.S. Cl.
CPC ...
514 25 ; 514-2 ; 514-8 ; 514 23 ; 536-111 ; 536-41 ; 536 172 ; 536 175 ; 536 187 ;
Abstract

Glyco-amino acids and glycopeptides having three-dimensionally stable configurations are described. These glyco-amino acids and glycopeptides have glycoside functional groups, such as fucose and analogues and derivatives thereof, covalently bound to an amino acid or peptide having a free carboxylic group or sulfate group in an orientation that facilitates the binding between these groups and selectin receptors. The present glyco-amino acids and glycopeptides may be used in the treatment of selectin-mediated disorders, such as inflammation, autoimmune disease and cancer.


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