The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 1997

Filed:

Feb. 12, 1996
Applicant:
Inventors:

Patricia D Murphy, Slingerland, NY (US);

Antonette C Allen, Millersville, MD (US);

Christopher P Alvares, Potomac, MD (US);

Brenda S Critz, Frederick, MD (US);

Sheri J Olson, Arlington, VA (US);

Denise B Schelter, Burtonsville, MD (US);

Bin Zeng, Rockville, MD (US);

Assignee:

OncorMed, Inc., Gaithersburg, MD (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12P / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435 912 ; 536 231 ; 536 243 ; 536 2433 ;
Abstract

A consensus DNA sequence has been determined for the BRCA1 gene. As has been seven polymorphic sites and their rates of occurrence in normal BRCA1 genes. The consensus gene BRCA1.sup.(omi) and the seven polymorphic sites will provide greater accuracy and reliability for genetic testing. One skilled in the art will be better able to avoid misinterpretations of changes in the gene, determine the presence of a normal gene, and of mutations, and to classify tumors.


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