The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 1997

Filed:

Mar. 14, 1994
Applicant:
Inventors:

Elise C Kohn, Olney, MD (US);

Lance A Liotta, Potomac, MD (US);

Young Sook Kim, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ; C12N / ;
U.S. Cl.
CPC ...
514 44 ; 536 231 ; 536 232 ; 536 235 ; 435 911 ; 435 915 ; 4351723 ; 4353201 ; 935-9 ; 935 14 ;
Abstract

This invention provides for nucleotide sequences that encode CAIR proteins correlated with cellular resistance to carboxyamido-triazole (CAI) and functionally equivalent compounds. The invention further provides for methods of detecting CAI resistance in biological samples and for cell lines that grow and proliferate in the presence of CAI and functionally equivalent compounds.


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