The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 1997

Filed:

Jul. 26, 1993
Applicant:
Inventor:

Massimo Porro, Siena, IT;

Assignee:

BiosYnth S.r.l., Siena, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
514 11 ; 514 12 ; 514 14 ; 514 15 ; 514 16 ; 514 17 ; 530324 ; 530327 ; 530328 ; 530329 ; 530350 ; 530317 ;
Abstract

The present invention is concerned with a peptide composition which includes a peptide having units of the formula: (a) (A).sub.n wherein A is Lysine or Arginine and n is an integer with a minimum value of 7. (b) (AB).sub.m wherein A is Lysine or Arginine and B is a hydrophobic amino acid selected from the group consisting of Valine, Leucine, Isoleucine, Tyrosine, Phenylalanine and Tryptophan; m is an integer with a minimum value of 3; and (c) (ABC).sub.p wherein A is a cationic amino acid which Is Lysine or Arginine; B and C are hydrophobic amino acids which may be the same or different and are selected from the group consisting of Valine, Leucine, Isoleucine, Tyrosine, Phenylalanine and Tryptophan; p is an integer with a minimum value of 2. The compositions of the invention bind Lipid-A of endotoxins.


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