The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 1997
Filed:
May. 02, 1995
Applicant:
Inventors:
Kyung Jin Kim, San Francisco, CA (US);
Michael A Horton, Nr Saffron Walden, GB;
Sarah C Bodary, San Francisco, CA (US);
Anan Chuntharapai, Colma, CA (US);
Assignee:
Genentech, Inc., So. San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; G01N / ; C12N / ; C07K / ;
U.S. Cl.
CPC ...
435-71 ; 4241431 ; 4241411 ; 435334 ; 435332 ; 5303881 ;
Abstract
The invention relates to monoclonal antibodies to the .alpha.v.beta.3 integrin receptor known to be expressed in large amounts on the surface of osteoclasts and accordingly, associated with bone resorption. The disclosed monoclonal antibodies are believed to recognize unique epitopes on .alpha.v.beta.3 and are useful in the treatment of conditions associated with excessive bone resorption and/or in the inhibition of tumor cell growth.