The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 1997
Filed:
Dec. 12, 1995
Applicant:
Inventors:
Arthur J Elliott, Aiken, SC (US);
David A Walsh, Birmingham, AL (US);
Assignee:
BioCryst Pharmaceuticals, Inc., Birmingham, AL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07F / ; C07C / ;
U.S. Cl.
CPC ...
544280 ; 544117 ; 544238 ; 544244 ; 546330 ; 548251 ; 548253 ; 548254 ; 548255 ; 5482644 ; 5482648 ; 5482672 ; 549 77 ; 558386 ; 558401 ; 558404 ; 558405 ; 558406 ; 558410 ; 558428 ; 558429 ; 558430 ; 558432 ;
Abstract
Derivatives of 9-deazaguanine are prepared by reacting an aldehyde or ketone with a dialkylaminomalonate to form the corresponding enamine. The enamine is then reacted with a base to form a cyclic pyrrole. The cyclic pyrrole is reacted with an urea compound to provide a protected guanidino compound. The guanidino is converted to the desired 9-deazaguanine derivative by reacting with trifluoracetic acid or with an alkoxide or hydroxide followed by neutralization with an acid.
Elliott, Arthur. (1997). Process for the preparation of 9-deazaguanine derivatives (U.S. Patent No. 5650511). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5650511
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile