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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5650503 B1

PDFFull Text
Date of Patent:
Jul. 22, 1997

Filed:

Dec. 20, 1994

Genetic construct of which protein coding dna comprises introns and is

Applicant:
Inventors:

Alan Langskill Archibald, Edinburgh, GB;

Anthony John Clark, Lasswade, GB;

Stephen Harris, Edinburgh, GB;

Margaret McClenaghan, Edinburgh, GB;

Jonathan Paul Simons, Edinburgh, GB;

Christopher Bruce Whitelaw, Edinburgh, GB;

Assignee:

PPL Therapeutics (Scotland) Limited, Edinburgh, GB;

Attorney:

Sterne, Kessler, Goldstein & Fox, P.L.L.C.

Primary Examiner:

Christopher S Low

Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 235 ; 536 232 ; 536 234 ; 536 2351 ; 536 231 ; 536 241 ; 536 242 ; 800-2 ; 4353201 ; 4351723 ; 4352402 ; 435 914 ; 4352523 ; 935 14 ; 935 22 ; 935 32 ; 935 70 ; 935-9 ; 935 10 ; 935 11 ; 935 13 ;
Abstract

Proteinaceous products can be produced by transgenic animals having genetic constructs integrated into their genome. The construct comprises a 5'-flanking sequence from a mammalian milk protein gene (such as beta-lactoglobulin) and DNA coding for a heterologous protein other than the milk protein (for example a serin protease such as alpha.sub.1 -antitrypsin or a blood factor such as Factor VIII or IX). The protein-coding DNA comprises at least one, but not all, of the introns naturally occurring in a gene coding for the heterologous protein. The 5'-flanking sequence is sufficient to drive expression of the heterologous protein.

Find Patent Forward Citations

Archibald, Alan. (1997). Genetic construct of which protein coding dna comprises introns and is (U.S. Patent No. 5650503). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5650503

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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