The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 1997

Filed:

May. 17, 1995
Applicant:
Inventors:

Pier Lucio Anelli, Milan, IT;

Christoph De Haen, Milan, IT;

Luciano Lattuada, Milan, IT;

Pierfrancesco Morosini, Milan, IT;

Fulvio Uggeri, Milan, IT;

Assignee:

Dibra S.p.A., Milan, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B / ;
U.S. Cl.
CPC ...
1286534 ; 424-93 ;
Abstract

Novel paramagnetic metal ion chelates and their use as contrast agents in the diagnostic technique known as 'magnetic resonance imaging' (M.R.I.) of the gastrointestinal tract and particularly of the liver, are described. The novel compounds result from the conjugation of a bile acid with a chelating agent and are capable of chelating the ions of bivalent and trivalent metals. The compounds have formula A-L-B in which A is the residue of a bile acid and derivatives of a bile acid, B is the residue of a chelating agent of a bivalent or trivalent metal ion having an atomic number of 20 to 31, 39, 42, 43, 44, 49, 57 to 83, L is a ligand between A and B.


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