The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 1997
Filed:
Mar. 29, 1995
Applicant:
Inventors:
Mineo Niwa, Muko, JP;
Yoshimasa Saito, Osaka, JP;
Hitoshi Sasaki, Amagasaki, JP;
Masako Hayashi, Takatsuki, JP;
Jouji Notani, Takatsuki, JP;
Masakazu Kobayashi, Ikeda, JP;
Assignee:
Fujisawa Pharmaceutical Co., Ltd., Osaka, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07H / ; A61K / ;
U.S. Cl.
CPC ...
4351723 ; 435212 ; 4353201 ; 536 232 ; 514 12 ;
Abstract
The invention relates to a new tissue plasminogen activator which has strong activity for converting plasminogen into plasmin that degrades the fibrin network of blood clots to form soluble products and therefore is useful as a thrombolytic agent. The invention also relates to a DNA sequence encoding the amino acid sequence for the tissue plasminogen activator, to a process for producing the plasminogen activator, and to a pharmaceutical composition comprising the new tissue plasminogen activator.