The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 1997

Filed:

Aug. 12, 1994
Applicant:
Inventors:

Hans Albertsen, Salt Lake City, UT (US);

Rakesh Anand, Cheshire, GB;

Mary Carlson, Salt Lake City, UT (US);

Joanna Groden, Salt Lake City, UT (US);

Philip John Hedge, Cheshire, GB;

Geoff Joslyn, Salt Lake City, UT (US);

Kenneth Kinzler, Baltimore, MD (US);

Alexander Markham, Cheshire, GB;

Yusuke Nakamura, Tokyo, JP;

Andrew Thliveris, Salt Lake City, UT (US);

Bert Vogelstein, Baltimore, MD (US);

Raymond L White, Salt Lake City, UT (US);

Assignees:

The John Hopkins University, Baltimore, MD (US);

University of Utah, Salt Lake City, UT (US);

Japanese Foundation for Cancer Research Cancer Institute, Tokyo, JP;

Zeneca Limited, Cheshire, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C12P / ; C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 435 911 ; 435 912 ; 536 235 ; 536 2431 ; 536 2433 ; 935 77 ; 935 78 ;
Abstract

Methods are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. APC is a tumor suppressor.


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