The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 1997

Filed:

Jun. 14, 1996
Applicant:
Inventors:

Jia-Li Liao, San Pablo, CA (US);

Stellan Hjerten, Upsala, SE;

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D / ;
U.S. Cl.
CPC ...
2101982 ; 2105021 ; 210635 ; 210656 ; 95 88 ; 96101 ; 502439 ;
Abstract

A separation medium for reversed-phase chromatography is prepared by polymerizing an aqueous vinyl monomer mixture to which a hydrophobic alkyl methacrylate with 3 or more carbon atoms in the alkyl group and a detergent have been added. The further inclusion of a vinyl monomer with a charged group in the reaction mixture produces a separation medium useful for reversed-phase electrochromatography. Performance of the polymerization in a capillary produces a continuous bed inside the capillary. An alternative for non-capillary separations, such as those conducted in larger diameter tubing, is the preparation of the medium in a vessel outside the tubing, followed by granulation of the polymer and placement of the granules in the tubing.


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