The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 1997

Filed:

Oct. 16, 1995
Applicant:
Inventors:

Wilhelmus Antonius Berbers, Utrecht, NL;

Petrus Theodorus Biessels, Oegstgeest, NL;

Willem Karel Bleeker, Amsterdam, NL;

Joachim Cornelis Bakker, Koog aan de Zaan, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ;
U.S. Cl.
CPC ...
530385 ;
Abstract

The described invention relates to an essentially stroma-free hemoglobin composition evidencing properties suitable for use as a universally applicable blood plasma expander and to a method for the preparation thereof. Typical, of these properties are desirable oxygen affinity values, desirable vascular retention time and substantial absence of toxic side effects. The described composition comprises human hemoglobin cross-linked intramolecularly through the beta-chains and polymerized with glutaraldehyde. Intramolecular cross-linking is typically effected with 2-nor-2-formylpyridoxal 5-phosphate or a bis-pyridoxal polyphosphate.


Find Patent Forward Citations

Berbers, Wilhelmus. (1997). Hemoglobin composition and preparation thereof (U.S. Patent No. 5646252). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5646252

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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