The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 1997
Filed:
Jun. 07, 1995
Applicant:
Inventors:
James M Roberts, Seattle, WA (US);
Motoaki Ohtsubo, Seattle, WA (US);
Andrew C Koff, Seattle, WA (US);
Frederick Cross, New York, NY (US);
Assignee:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; G01N / ;
U.S. Cl.
CPC ...
435-74 ; 435-4 ; 435-71 ; 435-78 ; 435 15 ; 436 63 ;
Abstract
Whole cell or cell-free test systems for screening and identifying compounds that modulate or alter Cyclin E activity. Whole cell assays measure the G1 phase of cells in the presence or absence of the test compound. Additional whole cell or cell-free assays measure binding of cyclin E to a cell division kinase, measure cyclin E activity directly, or measure the cell division kinase activity directly in the presence or absence of the test compound.