The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 1997

Filed:

Aug. 04, 1994
Applicant:
Inventors:

Meihan Nonoyama, St. Petersburg, FL (US);

Akiko Tanaka, Clearwater, FL (US);

Patrick K Lai, Clearwater, FL (US);

Assignee:

Tampa Bay Research Institute, St. Petersburg, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C12P / ;
U.S. Cl.
CPC ...
514 21 ; 435 704 ; 530350 ;
Abstract

A protein having potent anti-HIV activity is obtained by a method which comprises culturing a strain of CD4-positive T cells, such as a subclone of CEM cells designated 4084, in a tissue culture medium under conditions in which the cells are induced to produce and secrete a protein having anti-HIV activity, separating the cells from the culture medium containing the protein and then recovering the protein from the medium, wherein the molecular weight of the protein having anti-HIV activity is at least 30,000 daltons as determined by a membrane with defined pore size that retains molecules of 30,000 daltons.


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