The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 1997
Filed:
Oct. 26, 1994
Applicant:
Inventors:
Reiko Namikawa, Palo Alto, CA (US);
Seishi Kyoizumi, Aki-gun, JP;
Emilya Shtivelman, Belmont, CA (US);
Joseph M McCune, San Francisco, CA (US);
Assignee:
Systemix, Inc., Palo Alto, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
424-91 ; 424-92 ; 424 931 ; 424 933 ; 424520 ; 424529 ; 424578 ; 424582 ; 424900 ; 4351723 ; 800-2 ;
Abstract
A method for initiating metastasis of human tumor cells under experimental conditions is provided. Immunocompromised non-human mammals having a viable, xenogeneic organ or tissue are used as a host for human tumor cells. The cells are introduced into the chimeric animal after the solid tissue is implanted and are then able to grow and metastasize as they would in situ. Therapeutic regimens may be evaluated in this system to determine efficacy against metastatic processes.