The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 1997
Filed:
Apr. 26, 1995
Shingou Sakurai, Mishima, JP;
Masanobu Naruto, Kamakura, JP;
Makoto Kihara, Mishima, JP;
Keizo Hanada, Yokohama, JP;
Emiko Sano, Yokohama, JP;
Shigeru Ichikura, Mishima, JP;
Jun Utsumi, Kamakura, JP;
Kazuo Hosoi, Sunto-gun, JP;
Toray Industries, Inc., Tokyo, JP;
Abstract
The present invention relates to compositions containing human interleukin-6 with sugar chains, a process for preparing human interleukin-6 by culturing cells in a medium containing ascorbic acid or any of its derivatives, and a process for purifying a crude raw human interleukin-6 solution by chromatography using a carrier with heparin bound. The present invention has allowed the production of high quality human interleukin-6 compositions with sugar chains, and their application to medicines. Furthermore, it has established a process for massproducing human interleukin-6.