The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 1997
Filed:
Oct. 07, 1994
Applicant:
Inventors:
Robert H Singer, Shrewsbury, MA (US);
Edward H Kislauskis, Kingston, MA (US);
Assignee:
University of Massachusetts Medical Center, Worcester, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; G07H / ;
U.S. Cl.
CPC ...
435325 ; 435375 ; 514 44 ; 536 231 ; 536 245 ; 935 33 ;
Abstract
Disclosed are the particular 3' noncoding nucleotide sequences (zipcode and zipcode elements) that cause .beta.-actin mRNA (and .beta.-actin protein synthesis) to be localized in specific regions of the cytoplasm. Also disclosed is the discovery that zipcode function can be fully inhibited by antisense oligonucleotides.