The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 1997
Filed:
May. 26, 1995
Ryoichi Ando, Machida, JP;
Naoko Ando, Machida, JP;
Hirokazu Masuda, Yokohama, JP;
Yasuhiro Morinaka, Tsuchiura, JP;
Chizuko Takahashi, Yokohama, JP;
Yoshikuni Tamao, Machida, JP;
Akihiro Tobe, Yokohama, JP;
Mitsubishi Chemical Corporation, Tokyo, JP;
Abstract
A novel ketone derivative (I) which possesses a potent inhibitory activity against thiol protease such as papain, cathepsin B, cathepsin H, cathepsin L, calpain or the like with excellent properties regarding oral absorbance, tissue transference and cell membrane permeability, and are clinically useful in the treatment of various diseases such as muscular dystrophy, amyotrophy. Also provided are a process for producing the compound (I) and a pharmaceutical composition containing the same.