The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 1997
Filed:
Dec. 02, 1993
Applicant:
Inventors:
Christopher K Mirabelli, Dover, MA (US);
David J Ecker, Leucadia, CA (US);
Timothy A Vickers, Oceanside, CA (US);
Debra L Robertson, Del Mar, CA (US);
Assignee:
Isis Phamaceuticals, Inc., Carlsbad, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435-5 ; 4351723 ; 536 241 ; 536 243 ; 536 2432 ;
Abstract
Methods for identifying oligonucleotides having a desired activity in vivo are disclosed. In accordance with preferred embodiments, oligonucleotides capable of conferring a desired phenotype are identified. Therapeutic, diagnostic and research methods and compositions employing such oligonucleotides are provided. Prior knowledge of the sequence or structure of a target molecule is generally not required.