The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 1997

Filed:

Jun. 02, 1995
Applicant:
Inventors:

Mitsunori Ono, Lexington, MA (US);

Y-S. Edmond Cheng, Wayland, MA (US);

Douglas F Marks, Jr, Sommerville, MA (US);

Hiroshi Kataguchi, Hatano, JP;

Assignee:

Fuji ImmunoPharmaceuticals Corp., Lexington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514250 ; 514251 ; 435238 ; 544347 ; 544348 ;
Abstract

Disclosed are chemical agents with unexpected antimicrobial activity against the microbes, especially Porphyromonas gingivalis, known to be important in the cause and progression of gingivitis, periodontitis, and destruction of hard and soft oral tissues leading to tooth loss. The agents have additional unexpected anticollagenase activity useful in the direct mitigation of tissue damage. The agents can be formulated to produce various compositions and dental implements useful in management of peridental diseases, particularly those involving infection with certain gram-negative anaerobes.


Find Patent Forward Citations

Loading…