The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 1997

Filed:

Aug. 16, 1994
Applicant:
Inventors:

Glenn F Spaulding, Houston, TX (US);

Thomas J Goodwin, Friendswood, TX (US);

Kim C O'Connor, New Orleans, LA (US);

Karen M Francis, Aiken, SC (US);

Angela D Andrews, Pensacola, FL (US);

Tacey L Prewett, Friendswood, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ;
U.S. Cl.
CPC ...
435 691 ; 4353201 ; 4351723 ; 435 692 ; 435 693 ; 435 694 ; 435 695 ; 435 6951 ; 435 6952 ; 435 696 ; 435 697 ; 536 231 ; 935 33 ; 935 34 ; 935 60 ; 935 66 ; 935 70 ;
Abstract

A process has been developed for recombinant production of selected polypeptides using transformed insect cells cultured in a horizontally rotating culture vessel modulated to create low shear conditions. A metabolically transformed insect cell line is produced using the culture procedure regardless of genetic transformation. The recombinant polypeptide can be produced by an alternative process using virully infected or stably transformed insect cells containing a gene encoding the described polypeptide. The insect cells can also be a host for viral production.


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