The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 1997
Filed:
Feb. 03, 1994
Applicant:
Inventors:
Barry L Karger, Newton, MA (US);
William G Thilly, Winchester, MA (US);
Frantisek Foret, Malden, MA (US);
Konstaintin Khrapko, Brookline, MA (US);
Phouthone Koehavong, Pittsburgh, PA (US);
Aharon S Cohen, Newton, MA (US);
Roger W Giese, Quincy, MA (US);
Assignees:
Massachusetts Institute of Technology, Cambridge, MA (US);
Northeastern University, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 435 18 ; 4351731 ; 4352831 ; 4352851 ; 4352871 ; 4352872 ; 4352891 ; 435810 ; 422 681 ; 436501 ; 536 221 ; 536 253 ; 536 254 ; 935 77 ; 935 78 ; 935 88 ;
Abstract
The disclosure relates to a method for resolving double-stranded DNA species differing by at least one base pair. Each of the species is characterized by an iso-melting domain with a unique melting temperature contiguous with a melting domain of higher thermal stability.