The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 1997
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Katsuyoshi Iwamatsu, Kanagawa, JP;
Yasuo Sato, Kanagawa, JP;
Masaaki Izumi, Kanagawa, JP;
Fukio Konno, Kanagawa, JP;
Seiji Shibahara, Kanagawa, JP;
Shigeharu Inoye, Kanagawa, JP;
Koichi Shudo, Tokyo, JP;
Kazuko Amano, Kanagawa, JP;
Assignees:
Meiji Seika Kaisha, Ltd., Tokyo, JP;
Koichi Shudo, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514254 ; 514218 ; 544361 ; 544368 ; 540575 ;
Abstract
A benzoxazole derivative of the formula (1) or (2) which has an alicyclic diamine group at the 2-position: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, X.sup.-, m and n are defined herein. The compound shows excellent 5-HT.sub.3 receptor antagonism and is useful as an antiemetic agent, a peristalsis controlling agent, an analgesic agent, an antianxiety agent and a schizophrenia treating agent.