The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 1997

Filed:

Feb. 16, 1993
Applicant:
Inventors:

Gail P Mazzara, Winchester, MA (US);

Dennis L Panicali, Acton, MA (US);

Bryan Roberts, Cambridge, MA (US);

Linda R Gritz, Somerville, MA (US);

Virginia Stallard, Sequim, WA (US);

Anna Mahr, Natick, MA (US);

Assignee:

Therion Biologics, Incorporated, Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
435236 ; 435 691 ; 435 693 ; 4351723 ; 4353201 ; 930221 ;
Abstract

Recombinant avipox viral vectors which express heterologous polypeptides capable of assembling into defective nonself-propagating viral particles are disclosed. The recombinant avipox viruses can be used to produce significant amounts of the heterologous polypeptides in avian or non-avian cells. Preferably, the recombinant avipox virus is a fowlpox virus. The viral particles can also be used as immunogens and for targeted delivery of heterologous gene products and drugs.


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