The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 1997
Filed:
Jun. 23, 1994
Applicant:
Inventors:
Daniel E Kahne, Princeton, NJ (US);
Suzanne W Kahne, Princeton, NJ (US);
Michael J Sofia, Laurenceville, NJ (US);
Nicole T Hatzenbuhler, Kendall Park, NJ (US);
Assignees:
Trustees of Princeton University, Princeton, NJ (US);
Transcell Technologies, Inc., Monmouth Junction, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07J / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
536-5 ; 536 231 ; 536 241 ; 536 243 ; 514 26 ; 514 44 ;
Abstract
Novel glycosylated steroid derivatives for facilitating the transport of compounds across biological membranes, either in admixture or as conjugates, are disclosed. A novel process for efficient synthesis of these glycosylated steroid derivatives, using activated glycosyl sulfoxide intermediates is provided. Methods for the permeabilization of membranes and the enhancement of the activity of predetermined compounds are also provided.