The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 1997

Filed:

Jan. 23, 1996
Applicant:
Inventors:

Rolf Graeve, Taunustein, DE;

Werner Thorwart, Hochheim, DE;

Ruth Raiss, Frankfurt, DE;

Klaus U Weithmann, Hofheim, DE;

Stefan M ullner, Hochheim, DE;

Assignee:

Hoechst Aktiengesellschaft, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07F / ; C07F / ;
U.S. Cl.
CPC ...
514120 ; 514 89 ; 514 90 ; 514 95 ; 514100 ; 514105 ; 514112 ; 514114 ; 544157 ; 546 22 ; 549-7 ; 549220 ; 556 19 ;
Abstract

Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders Compounds of the formula I ##STR1## are suitable for producing pharmaceuticals for the treatment and prophylaxis of degenerative joint disorders, of rheumatic disorders accompanied by cartilage breakdown, such as rheumatoid arthritis, joint trauma and chondrolysis as a consequence of prolonged immobilization of the joint, of inflammations, septic shock, disorders with impaired leukocyte adhesion, disorders caused by an elevated concentration of tumor necrosis factor alpha, such as cachexia or Crohn's disease.


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