The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 1997

Filed:

Jul. 20, 1994
Applicant:
Inventors:

Ricardo Miledi, Irvine, CA (US);

Larry E Overman, Corona del Mar, CA (US);

Yoshinori Murata, Irvine, CA (US);

Richard M Woodward, Aliso Viejo, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F / ; A61K / ;
U.S. Cl.
CPC ...
514 89 ; 546 21 ;
Abstract

Novel phosphinic and phosphonic acid derivatives of pyridine, pyrrole and azepine with utility as antagonists of the GABA.sub.rho receptor are disclosed. These compounds have utility as modulators of the excitability of the central nervous system as mediated by their ability to specifically act on closed-channel binding sites of GABA.sub.rho receptors.


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